发表论文概述
lMengxue Sun, Haoyuan Feng, Xuefei Sun, Ruiyang Bai, Feng Feng, Qilong Li, Hongxia Sun,* Li Yao.* G-Quadruplex-Modular CpG nanoplatform drives multi-pathway immunity for abscopal chemoimmunotherapy. Adv. Mater. 2026, DOI:10.1002/adma.72908.
lQilong Li, Wangqing Li, Xuefei Sun, Feng Feng, Zhengdong Cheng, Wenchao Li,* Li Yao,* Xiuyu Wang.* Modular biosurface engineering of magnetotactic bacteria for multimodal synergistic cancer therapy. Chem. Bio. Eng. 2026, 3, 524-534.
l Feng Feng, Wangqing Li, Qilong Li, Xuefei Sun, Zhengdong Cheng, Xiuyu Wang,* Wenchao Li,* Li Yao.* A polymer-free, tumor-microenvironment responsive sol-gel platform for spatiotemporal STING activation and self-amplifying immunotherapy. Mater. Horiz. 2025, 12, 9562-9569.
l Bin Zhao, Ting Lei, Wang Xiang, Xiaojie Zhang, Libo Du,* Li Yao, Zheng Sun, Maofa Ge, Weigang Wang.* Toxicity of biogenic secondary organic aerosol toward nerve cells. Chem. Res. Toxicol. 2025, 38, 1585-1594.
l Xueyan Feng, Di Zhang, Guoxun Wang, Liwei Lu, Feng Feng, Xiuyu Wang, Chanchan Yu, Yahong Chai, Jin Zhang, Wenchao Li, Jing Liu, Hongxia Sun,* Li Yao.* Mechanisms and therapeutic strategies for minority cell-induced paclitaxel resistance and tumor progression mediated by mechanical forces. Adv. Sci. 2025, 12, 2417805.
l Dawei Yang, Ranran Sun, Hongxia Sun,* Qian Li, Hong Zhang, Xiufeng Zhang, Lei Shi, Li Yao,* Yalin Tang.* A FRET biosensor constructed using pH sensitive G-quadruplex DNA for detecting mitochondrial autophagy. Talanta 2025, 281, 126885.
l Dawei Yang, Hongxia Sun,* Ranran Sun, Haoyuan Feng, Ruiyang Bai, Qian Li, Li Yao,* Yalin Tang.* A versatile biosensor for detecting Zn2+ and Cu2+ in Alzheimer’s disease cells and acidic foods via RNA G-quadruplex hydrolysis. J. Hazard. Mater. 2025, 490, 137847.
l Bingzhe Wang, Qilong Li, Yang Du, Qiyue Wang, Zeyu Liang, Mengmeng Li, Canyu Huang, Li Yao, Guangyuan Shi, Jie Tian,* Fangyuan Li,* Daishun Ling.* Ligand-mediated acid-activatable magnetic particle imaging probes for highly sensitive diagnosis of sepsis. Matter 2025, 8, 101957.
l Ranran Sun, Dawei Yang, Xiufeng Zhang, Jun Liu, Meirong Liu, Lixia Wang, Li Yao, Yalin Tang,* Hongxia Sun.* A fluorescent probe for rapid staining and real-time detection of autophagy in single cells by lighting-up G-quadruplexes. Sens. Actuat. B Chem. 2025, 423, 136768.
l Ruili Wang, Mengmeng Li, Xuefei Sun, Qianrui Lv,* Xiuyu Wang,* Li Yao.* MRI-visualized aqueous microenvironment engineering in 3D hierarchical FePt catalysts with macroporous architecture for alkaline hydrogen evolution. Nano Lett. 2025, 25, 12001-12008.
l Fanru Zhong, Ranran Sun, Saipeng Huang, Pengqi Guo,* Qian Li, Lixia Wang, Hongxia Sun,* Li Yao.* Determination of ligand selectivity to G-tetrad through an AMCA fluorescence quenching approach. Talanta 2024, 280, 126732.
l Ranran Sun, Hongxia Sun,* Xiongjun Ye, Dawei Yang, Boyang Zhang, Yan Liu, Ruiyang Bai, Fanru Zhong, Li Yao,* Yalin Tang.* A benzothiazole derivative for differentiating mitochondrial G-quadruplexformation between normal and tumor cells. Sens. Actuat. B Chem. 2024, 408, 135524.
l Ruiyang Bai, Dawei Yang, Ranran Sun, Xiufeng Zhang a,* Lei Shi, Jing Liu, Hongxia Sun,* Li Yao,* Yalin Tang. A supramolecular fluorescence probe that simultaneously responds to viscosity and G-quadruplex for autophagy detection. Anal. Chim. Acta 2024, 1329, 343245.
l Hongxia Sun, Ranran Sun, Dawei Yang, Qian Li, Wenna Jiang, Tianxing Zhou, Ruiyang Bai, Fanru Zhong, Boyang Zhang, Junfeng Xiang, Jing Liu,* Yalin Tang,* Li Yao.* A cyanine dye for highly specific recognition of parallel G‑quadruplex topology and its application in clinical RNA detection for cancer diagnosis. J. Am. Chem. Soc. 2024, 146, 22736-22746.
l Mengxue Sun, Hongxia Sun, Chanchan Yu, Pan Lu, Feng Feng, Jin Zhang,* Wenchao Li,* Li Yao.* Force-encoding DNA nanomachines for simultaneous and direct detection of multiple pathogenic bacteria in blood. Anal. Chem. 2024, 96, 4314-4321.
l Yuting Tang, Feng Feng, Guanhua Xu, Shijie Qin, Xiaoping Ouyang, Li Yao,* Xiuyu Wang.* Providing insight into exchange coupling within nanomagnetism: mechanism, micromagnetic simulation, synthesis and biomedical application. Sci. China Mater. 2024, 67(10), 3049-3082.
l Feng Feng, Qilong Li, Xuefei Sun, Li Yao,* Xiuyu Wang.* Tumor microenvironment-responsive magnetotactic bacteria-based multi-drug delivery platform for MRI-visualized tumor photothermal chemodynamic therapy. Biology 2024, 13, 658.
l Feng Feng, Yajing Liu,* Li Yao, Xiuyu Wang.* An enzyme mimicking dendritic platinum-iron oxide catalyzes the production of reactive oxygen species. Catalysts 2024, 14, 858.
l Boyang Zhang, Ranran Sun, Ruiyang Bai, Zhicheng Sun, Ruping Liu,* Wenchao Li,* Li Yao, Hongxia Sun,* Yalin Tang. G-quadruplex in mitochondria as a possible biomarker for mitophagy detection. Int. J. Biol. Macromol. 2024, 259, 129337.
l Qilong Li, Feng Feng, Min Xu, Yajing Liu, Mengmeng Li, Xueyan Feng, Xiuyu Wang,* and Li Yao.* Multifunctional liquid microrobots based on paramagnetic microdroplets. Cell Rep. Phys. Sci. 2023, 4, 101279.
l Dan Zhao, Shibo Peng, Hanzhang Xiao, Qilong Li, Yahong Chai, Hongxia Sun, Ruping Liu,* Li Yao,* Lin Ma. High-performance T1−T2 dual-modal MRI contrast agents through interface engineering. ACS Appl. Bio Mater. 2023, 6, 2137-2144.
l Jinxiu Zhan, Di Zhang, Feng Feng, Min Xu, Li Yao.* Homotypic and heterotypic adhesion of cancer cells revealed by force-induced remnant magnetization spectroscopy. Nanoscale Horiz. 2023, 8 (8), 1098-1105.
l Fengmin Yang, Dawei Yang, Lixia Wang, Qian Li*, Hong Zhang, Li Yao, Hongxia Sun,* Yalin Tang.* An inner salt derivative of Thioflavin T designed for live-cell imaging of mitochondrial G-quadruplexes. Sens. Actuat. B Chem. 2023, 374, 132820.
l Dawei Yang, Hongxia Sun,* Ranran Sun, Yan Liu, Hong Zhang, Lixia Wang, Li Yao,* Yalin Tang.* A supramolecular biosensor for monitoring lysosomal DNase activity in vivo and identifying tumor cells by responding to G-quadruplex hydrolysis. Sens. Actuat. B Chem. 2023, 384, 133664.
l Ranran Sun, Xiaomeng Guo, Dawei Yang, Xinchen Cai, Qian Li, Li Yao,* Hongxia Sun,* Yalin Tang.* RNA G-quadruplex in live cells lighted-up by a thiazole orange analogue for SCA36 identification. Int. J. Biol. Macromol. 2023, 229, 724-731.
l Wang Xiang, Weigang Wang,* Libo Du, Bin Zhao, Xingyang Liu, Xiaojie Zhang, Li Yao, Maofa Ge.* Toxicological effects of secondary air pollutants. Chem. Res. Chinese Universities 2023, 39(3), 326-341.
l Guanhua Xu, Mengmeng Li, Qiyue Wang, Feng Feng, Qi Lou, Yi Hou, Junfeng Hui, Peisen Zhang, Li Wang, Li Yao,* Shijie Qin, Xiaoping Ouyang, Dazhuan Wu, Daishun Ling,* Xiuyu Wang.* A dual-kinetic control strategy for designing nano-metamaterials: novel class of metamaterials with both characteristic and whole sizes of nanoscale. Adv. Sci. 2023, 10, 2205595.
l Mengxue Sun, Pan Lu, Chanchan Yu, Feng Feng, Qilong Li, Jinxiu Zhan, Min Xu, Yajing Liu, Li Yao.* Force-coded strategy for the simultaneous detection of multiple tumor-related proteins. Anal. Chem. 2022, 94, 8992-8998.
l Yajing Liu, Xiuyu Wang,* Feng Feng, Qilong Li, Hanzhang Xiao, Li Yao.* Deformable, sensible, and reconfigurable microgels with structural color: potential as camouflage soft microrobots. J. Mater. Chem. C 2022, 10, 5070-5078.
l Xue Han, Qi Lou, Feng Feng, Guanhua Xu, Song Hong, Li Yao,* Shijie Qin, Dazhuan Wu, Xiaoping Ouyang, Zhiguo Zhang, Xiuyu Wang.* Spatiotemporal release of reactive oxygen species and NO for overcoming biofilm heterogeneity. Angew. Chem. Int. Ed. 2022, 61, e202202559.
l Yahong Chai, Qi Lou, Min Xu, Song Hong, Feng Feng, Yajing Liu, Qilong Li, Xueyan Feng, Hanzhang Xiao, Ao Chen, Xiuyu Wang,* Li Yao.* Modulation of magnetic exchange coupling via constructing bi- or multimagnetic heterointerfaces. J. Phys. Chem. Lett. 2022, 13, 12082-12089.
l Shuyu Liao, Mengxue Sun, Jinxiu Zhan, Min Xu, Li Yao.* Advances in the biological application of force-induced remnant magnetization spectroscopy. Molecules 2022, 27, 2072.
l Feng Feng, Xueyan Feng, Di Zhang, Qilong Li, Li Yao.* Matrix stiffness induces pericyte-fibroblast transition through YAP activation. Front. Pharmacol. 2021, 12, 698275.
l Min Xu, Xueyan Feng, Feng Feng, Hantao Pei, Ruping Liu, Qilong Li, Chanchan Yu, Di Zhang, Xiuyu Wang, Li Yao.* Magnetic nanoparticles for the measurement of cell mechanics using force-induced remnant magnetization spectroscopy. Nanoscale 2020, 12, 14573-14580.
l Jinxiu Zhan, Feng Feng, Min Xu, Li Yao,* Maofa Ge.* Progress in chemo–mechanical interactions between nanoparticles and cells. Acta Phys. -Chim. Sin. 2020, 36, 1905076.
l Yahong Chai, Feng Feng, Qilong Li, Chanchan Yu, Xueyan Feng, Pan Lu, Xiuyu Wang,* Li Yao.* One-pot synthesis of high-quality bimagnetic core/shell nanocrystals with diverse exchange coupling. J. Am. Chem. Soc. 2019, 141, 3366-3370.
l Qilong Li, Haitao Chen, Xueyan Feng, Chanchan Yu, Feng Feng, Yahong Chai, Pan Lu, Tao Song, Xiuyu Wang,* Li Yao.* Nanoparticle-regulated semiartificial magnetotactic bacteria with tuneable magnetic moment and magnetic sensitivity. Small 2019, 15, 1900427.
l Xueyan Feng, Chanchan Yu, Feng Feng, Pan Lu, Yahong Chai, Qilong Li, Di Zhang, Xiuyu Wang, Li Yao.* Direct measurement of through-bond effects in molecular multivalent interactions. Chem. Eur. J. 2019, 25(12), 2978-2982.
l Chanchan Yu, Di Zhang, Xueyan Feng, Yahong Chai, Pan Lu, Qilong Li, Feng Feng, Xiuyu Wang, Yao Li.* Nanoprobe-based force spectroscopy as a versatile platform for probing the mechanical adhesion of bacteria. Nanoscale 2019, 11, 7648-7655.
l Di Zhang, Feng Feng, Ruping Liu, Wenjia Zhu, Li Yao.* Mechanochemistry in cancer cell metastasis. Chin. Chem. Lett. 2019, 30, 7-14.
l Hongbo Chen, Hongxia Sun,* Yahong Chai, Suge Zhang, Aijiao Guan, Qian Li, Li Yao,* Yalin Tang.* Insulin-like growth factor type I selectively binds to G-quadruplex structures. Biochim. Biophys. Acta Gen. Subj. 2019, 1863(1), 31-38.
l Pan Lu, Di Zhang, Yahong Chai, Chanchan Yu, XiuyuWang, Yalin Tang, Maofa Ge, Li Yao.* Regulatory-sequence mechanical biosensor: A versatile platform for investigation of G-quadruplex/label-free protein interactions and tunable protein detection. Anal. Chim. Acta 2019, 1045, 1-9.
l Di Zhang, Feng Feng, Qilong Li, Xiuyu Wang, Li Yao.* Nanopurpurin-based photodynamic therapy destructs extracellular matrix against intractable tumor metastasis. Biomaterials 2018, 173, 22-33.
l Shan Jiang, Wei Wang, Yonghong Ding, Qiang Yu, Li Yao. Preparation and characterization of antibacterial microporous membranes fabricated by poly(AMS-co-DMAEMA) grafted polypropylene via melt-stretching method. Chin. Chem. Lett. 2018, 29, 390-394.
l Xueyan Feng, Xiuyu Wang,* Di Zhang, Feng Feng, Li Yao,* Guiping Ma.* One-step preparation of monodisperse multifunctional macroporous particles through a spontaneous physical process. Small 2018, 14, 1703570.
l Xiuyu Wang, Xueyan Feng, Guiping Ma, Di Zhang, Yahong Chai, Maofa Ge, Li Yao.* Dual-phase separation in a semi-confined system: monodispersed heterogeneous block copolymer membranes for cell encoding and patterning. Adv. Mater. 2017, 29, 1605932.
l Xiuyu Wang, Yi Hou, Li Yao,* Mingyuan Gao,* Maofa Ge. Generation, characterization, and application of hierarchically structured self-assembly induced by the combined effect of self-emulsification and phase separation. J. Am. Chem. Soc. 2016, 138, 2090-2093.
l Xiuyu Wang, Xueyan Feng, Guiping Ma, Li Yao,* Maofa Ge. Amphiphilic Janus particles generated via a combination of diffusion-induced phase separation and magnetically driven dewetting and their synergistic self-assembly. Adv. Mater. 2016, 28, 3131-3137.
l Pan Lu, Qibin Liu, Yuzhu Xiong, Qing Wang, Yuting Lei, Shengjun Lu,* Liwei Lu, Li Yao*. Nanosheets-assembled hierarchical microstructured Ni(OH)2 hollow spheres for highly sensitive enzyme-free glucose sensors. Electrochim. Acta 2015, 168, 148–156.
l Liwei Lu, Xiuyu Wang, Chuanxi Xiong, Li Yao*. Recent advances in biological detection with magnetic nanoparticles as a useful tool. Sci. China Chem. 2015, 58(5), 793–809.
l Li Yao, Shoujun Xu. Detection of magnetic nanomaterials in molecular imaging and diagnosis applications. Nanotechnol. Rev. 2014, 3(3), 247-268.
l Lashan De Silva, Li Yao, Shoujun Xu*. Mechanically resolving noncovalent bonds using acoustic radiation force. Chem. Commun. 2014, 50, 10786-10789.